This research project aims to develop the software and hardware for an autonomous network of Wireless Smart Sensors (WSS) designed to evaluate and collect structural performance data of space launch vehicles (LVs) during mid-flight. This data collection, and subsequent processing and diagnostics, will permit structural performance assessments without human intervention. This aspect is particularly important for LVs, as human-controlled measurements are impossible during the launch phase and unfeasible for a small crew to maintain during the rest of the mission. This technology can be used to further both NASA missions and commercial space flight ventures by more closely monitoring critical structural components of space LVs.